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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14362 |
AY 9944
|
Others | Others |
AY 9944 是特异性的胆固醇生物合成抑制剂。它抑制 7- 脱氢胆固醇 Δ7- 还原酶 (IC50:13 nM),导致胆固醇不足和 7DHC 积累。在高剂量下,它可在培养的胚胎中抑制固醇 Δ7-Δ8 异构酶,造成胆固醇 8-en-3β-ol 的积累。 | |||
T14362L |
AY 9944 dihydrochloride
|
Others | Others |
AY 9944 dihydrochloride 是一个中间体。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03605 |
CHOD Protein, Streptomyces sp., Recombinant (GST)
choA,Cholesterol isomerase,CHOD,Choles... |
Streptomyces | E. coli |
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product. CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 81.9 kDa and the accession number is P12676. |